This Research Topic will showcase advances in non-animal toxicology that improve the mechanistic understanding and predictive assessment of chemical safety.

Lorna Ewart has long been frustrated by the mismatch between animal and human toxicity data. All too often preclinical studies in rats and dogs will suggest a drug is safe, only for clinical trial ...

VivoSim Labs has launched non-animal toxicology models to enhance drug development, aligning with FDA's initiative to phase out animal testing. VivoSim Labs, Inc. has officially launched after ...

Only about one in ten candidates entering clinical trials make it to market. Many promising drugs fail in early-phase trials despite passing preclinical tests with flying colours. These setbacks are ...

The U.S. Environmental Protection Agency formalized several policy recommendations designed to reduce animal tests in pesticide safety. Even though progress has been made in developing non-animal ...

The VICT3R project is expanding its consortium by adding new beneficiaries and organisations to the network of contract research organisations (CROs) associated with the project. This expansion ...

AI-based approaches are increasingly capturing complex human disease biology directly, without the use of potentially confounding animal models. [ignatiev / Getty Images] The recent decision by the ...

Other countries, like the U.K, the United States and the European Union have all dedicated funding and detailed roadmaps to ...

The National Toxicology Program (NTP) has announced a new classification criterion that it says should require between 50% and 83% fewer animals to be used during testing to determine whether a ...

Experts from the Physicians Committee for Responsible Medicine traveled to San Diego, California, to attend the 2026 Society of Toxicology Annual Meeting to advance our work accelerating the ...